abstract：OBJECTIVE:The purpose of this study was to explore the clinical significance and biological function of long noncoding RNA CASC9 (CASC9) in esophageal squamous cell carcinoma (ESCC). PATIENTS AND METHODS:Quantitative Real-time PCR (qRT-PCR) was used to determine the expression of CASC9 in ESCC tissues and cell lines. ...

journal_title：European review for medical and pharmacological sciences

authors： Gao GD,Liu XY,Lin Y,Liu HF,Zhang GJ

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:To investigate the relationships between blood uric acid (BUA) level and the incidence, progression and deterioration of diabetic nephropathy (DN) in patients with type 2 diabetes mellitus (T2DM). PATIENTS AND METHODS:A total of fifty patients with T2DM alone whose glycosylated hemoglobin (HbA1c) were under ...

journal_title：European review for medical and pharmacological sciences

authors： Li GX,Jiao XH,Cheng XB

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:Urogenital atrophy is a degenerative process that may occur during menopause causing debilitating disorders and painful symptomatology. Estrogen therapy slows the onset of atrophy, but it requires ongoing therapy to maintain its effectiveness. To mitigate the degenerative evolutions associated with menopause,...

journal_title：European review for medical and pharmacological sciences

authors： Casarotti GA,Chiodera P,Tremolada C

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:Long non-coding RNA CRNDE (CRNDE) recently emerged as a carcinogenic promoter in various cancers including gastric cancer (GC). However, the functions and molecular mechanisms of CRNDE to GC are still largely unclear. The aim of this study was to investigate the clinical significance and functional mechanisms...

journal_title：European review for medical and pharmacological sciences

authors： Du DX,Lian DB,Amin BH,Yan W

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:To identify the expression changes of microRNA 93 (miR-93) in oxygen-glucose deprivation/reoxygenation (OGD/R) injury in cardiomyocytes and its mechanism of mediating OGD/R and inducing apoptosis. MATERIALS AND METHODS:Primary cardiomyocytes were extracted and OGD/R model in cardiomyocytes was established in...

journal_title：European review for medical and pharmacological sciences

authors： Yan LJ,Fan XW,Yang HT,Wu JT,Wang SL,Qiu CG

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:Vesicoureteral reflux (VUR) affects up to 1% of Caucasian children. Primary VUR is characterized by failure of the ureterovesicular junction to prevent urine from traveling in a retrograde fashion from the bladder to the ureters and the kidneys. Several reports in the literature describe the prevalence of thi...

journal_title：European review for medical and pharmacological sciences

authors： Capozza N,Gulia C,Heidari Bateni Z,Zangari A,Gigli S,Briganti V,Tursini S,Koh CJ,Gaffi M,Baldassarra S,Signore F,Porrello A,Piergentili R

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:MiR‑638 has been demonstrated to be correlated with several tumor progressions. However, the exact role of miRNA-638 in cervical cancer (CC) has not been investigated. The aim of present study was to explore the prognostic value of miR-638 in patients with CC and analyze molecular mechanisms of miR-638 in CC ...

journal_title：European review for medical and pharmacological sciences

authors： Wei H,Zhang JJ,Tang QL

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:To investigate the expression of long non-coding RNA CASC15 in gastric cancer tissue and its effect on the proliferation of gastric cancer cell line MKN28. MATERIALS AND METHODS:We found that expression of lncRNA CASC15 in gastric cancer tissue was higher than normal gastric epithelium through the TCGA and G...

journal_title：European review for medical and pharmacological sciences

authors： Yao XM,Tang JH,Zhu H,Jing Y

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to explore the effects of cerebral ischemic preconditioning which can decrease brain ischemia/reperfusion (I/R) injury by inhibiting endoplasmic reticulum (ER) stress-induced apoptosis. MATERIALS AND METHODS:The focal cerebral ischemia rat was selected as the experimental model....

journal_title：European review for medical and pharmacological sciences

authors： Hu YQ,Chen W,Yan MH,Lai JJ,Tang N,Wu L

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the impact of a new formulation of probiotic mouthwash (PM), using Biocult strong® dissolved in neutral mouthwash. PATIENTS AND METHODS:Forty-two patients with cardiovascular disease (CVD) or type 1 and type 2 diabetes were enrolled. Plaque Control Record (PCR) and Bleeding on Probing (BOP) were ...

journal_title：European review for medical and pharmacological sciences

authors： Bollero P,Di Renzo L,Franco R,Rampello T,Pujia A,Merra G,De Lorenzo A,Docimo R

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:This research focuses on the influence of linc-ITGB1 on the metastasis of hepatocellular carcinoma and further explores its underlying mechanism. PATIENTS AND METHODS:A total of 70 hepatocellular carcinoma patients were chosen for our study. RT-qPCR was used for detecting the expression level of linc-ITGB1 i...

journal_title：European review for medical and pharmacological sciences

authors： Yu WW,Wang K,Liao GJ

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:Fatty liver may induce various complications including chronic hepatitis or liver cirrhosis, and is frequently occurred in obesity individuals. Advanced glycosylation end products (AGEs) were known to play a critical role in multiple liver diseases. This study, therefore, aimed to study the effect of AGEs on ...

journal_title：European review for medical and pharmacological sciences

authors： Xiong DD,Zhang M,Li N,Gai JF,Mao L,Li M

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:To observe the effect of metformin on the tight junction of intestinal epithelial cells and its relevant mechanism. MATERIALS AND METHODS:Caco-2 cell monolayers were incubated with or without tumor necrosis factor-α (TNF-α) (10 ng/mL) in the absence or presence of indicated concentrations of metformin. Trans...

journal_title：European review for medical and pharmacological sciences

authors： Zhou HY,Zhu H,Yao XM,Qian JP,Yang J,Pan XD,Chen XD

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:Gliomas are accompanied with high mortality owning to their invasive peculiarity and vulnerability to drug resistance. miR-21 is a vital oncogenic miRNA that regulates drug resistance of tumor cells. This study aims to elucidate the function of miR-21 in human glioma cells resistant to carmustine (BCNU) and t...

journal_title：European review for medical and pharmacological sciences

authors： Wang GB,Liu JH,Hu J,Xue K

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to observe the expression of transforming growth factor-β1 (TGF-β1) in myocardial tissue and the concentration of serum B-type natriuretic peptide (BNP) in myocardial remodeling of Sprague-Dawley rats induced by isoproterenol (ISO) and the effects of carvedilol intervention. M...

journal_title：European review for medical and pharmacological sciences

authors： Yi R,Xiangyu G,Min S

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:Ischemic stroke risk rises with the increasing cardiovascular risk factors in patients with and without AF. How atrial fibrillation (AF) incrementally contributes to the risk for ischemic stroke with increasing age and multiple cardiovascular risk factors is unclear. Von Willebrand factor (vWF) is a biomarker...

journal_title：European review for medical and pharmacological sciences

authors： Zhang F,Yang XC,Jia XW,Tang XH,Wang Z,Wang ZQ

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:MiR-564 has been discovered to be abnormally expressed in human malignancy. Two recent studies suggested that miR-564 plays a role in tumor inhibition in both lung and breast cancer. However, no evidence reported the mechanism and function of miR-564 in prostate cancer (PCa). PATIENTS AND METHODS:The PCa tis...

journal_title：European review for medical and pharmacological sciences

authors： Meng FJ,Meng FM,Wu HX,Cao XF

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:Polycystic ovarian syndrome and obesity contribute to the metabolic complications for women of reproductive age. The aim of present study was to analyze the effect of abdominal obesity expressed using waist/hip ratio (WHR) in patients with polycystic ovary syndrome on metabolic parameters. PATIENTS AND METHO...

journal_title：European review for medical and pharmacological sciences

authors： Franik G,Bizoń A,Włoch S,Pluta D,Blukacz Ł,Milnerowicz H,Madej P

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:To investigate the therapeutic effect of drug therapy with cyclophosphamide and leflunomide on the joint function damage of patients with systemic lupus erythematosus (SLE) and its regulatory effects on expression levels of programmed death receptor 1, Notch signaling pathway genes and interferon-inducible pr...

journal_title：European review for medical and pharmacological sciences

authors： Zhou QS,Hu J,Hu H

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:To investigate and discuss the effect of early treatment with pulmonary surfactant (PS) on oxygenation functions in neonates with acute respiratory distress syndrome (ARDS), to understand the expression trend of serum transforming growth factor-beta 1 (TGF-β1) and bone morphogenetic protein 7 (BMP-7) in child...

journal_title：European review for medical and pharmacological sciences

authors： Wang LP,Mao QH,Yang L

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:MiR-595 has been demonstrated to be involved in tumorigenesis of several cancers. However, the clinical significance of miR-595 in epithelial ovarian cancer (EOC) remains unclear. The aim of this study was to explore the correlation of miR-595 expression with clinicopathologic features and prognosis in EOC pa...

journal_title：European review for medical and pharmacological sciences

authors： Zhou QH,Zhao YM,Jia LL,Zhang Y

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:Supplementation with Mirtogenol® improves the retinal microcirculation and reduces intraocular pressure (IOP) in ocular hypertension, when administrated either alone or in association with an ophthalmic solution (latanoprost). In this study, microcirculatory parameters (perfusion of the circle of Zinn-Haller ...

journal_title：European review for medical and pharmacological sciences

authors： Gizzi C,Torino-Rodriguez P,Belcaro G,Hu S,Hosoi M,Feragalli B

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:To explore the effects of remote ischemic preconditioning on myocardial injury and prognosis after percutaneous coronary intervention (PCI) in patients with acute coronary syndrome. PATIENTS AND METHODS:The study was a single center, prospective, randomized, controlled study. A total of 184 patients with uns...

journal_title：European review for medical and pharmacological sciences

authors： Zhou FZ,Song W,Yin LH,Song ZF,Yang S,Yang FB,Liu JF,Song YG,Zhang HY,Zhang ZM

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:To dissect the functioning mode of miR-645 on renal clear cell carcinoma cell metastasis and growth, and provide therapeutic targets for renal clear cell carcinoma. PATIENTS AND METHODS:Quantitative Real-time PCR (qRT-PCR) assay was employed to detect miR-645 expression level. Wound healing assay and transwe...

journal_title：European review for medical and pharmacological sciences

authors： Chen J,Shu Y,Yu Q,Shen W

更新日期：2017-10-01 00:00:00

abstract：:The purpose of this pictorial essay is to describe anatomic variants and congenital anomalies of portal venous system and related liver parenchymal alterations. The imaging findings of some of these entities have been previously described in other articles, however this work encompasses all congenital anomalies of por...

journal_title：European review for medical and pharmacological sciences

authors： Guerra A,De Gaetano AM,Infante A,Mele C,Marini MG,Rinninella E,Inchingolo R,Bonomo L

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:Cerebral infarction, or ischemia brain stroke, is a common cerebrovascular disease. Bone marrow mesenchymal stem cells (BMSCs) are widely used to treating ischemia disease such as cardiac infarction. Ultrasonic microvesicles may help the targeting of exogenous factors via localized energy blast. Therefore, th...

journal_title：European review for medical and pharmacological sciences

authors： Chang F,Xiong W,Wang D,Liu XZ,Zhang W,Zhang M,Jing P

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:lncRNA MEG3 has been reported as a tumor suppressor gene in many different kinds of cancer, but its role in gastric cancer has not been fully understood. Then, we would like to explore its mechanism in gastric cancer. PATIENTS AND METHODS:We first used qRT-PCR to detect the expression of lncRNA MEG3, then CC...

journal_title：European review for medical and pharmacological sciences

authors： Wei GH,Wang X

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:Endometrial carcinoma is the most common malignancy of the female genital tract. Therefore, there is an urgent need to understand the molecular mechanism of its metastasis. This study is aimed to explore the function and underlying mechanism of miR-326 in endometrial cancer (EC). PATIENTS AND METHODS:RT-PCR ...

journal_title：European review for medical and pharmacological sciences

authors： Liu W,Zhang B,Xu N,Wang MJ,Liu Q

更新日期：2017-10-01 00:00:00

abstract：:Many factors have been identified to influence the risk of mother to child transmission (MTCT) of HIV. Chief amongst these is high maternal VL and advanced disease. High maternal viral load (mVL), measured at delivery, has been described as the strongest risk factor for both in utero (IU) and intrapartum (IP) transmis...

journal_title：European review for medical and pharmacological sciences

authors： Liu JF,Liu G,Li ZG

更新日期：2017-10-01 00:00:00

abstract：:Advancements in pediatric cancers diagnostics clarity and treatments have greatly increased survival rates in the pediatric oncology population. Increased survival rates have turned new attention to studying psychosocial stressors and improvisation of the quality of life of the suffering cancer patients. The cancer tr...

journal_title：European review for medical and pharmacological sciences

authors： An Q,Fan CH,Xu SM

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:To investigate the role of hypoxia-inducible factor-1α and its target genes in hypoxic pulmonary hypertension in neonates. PATIENTS AND METHODS:A total of 117 newborns were selected and divided into two groups for clinical experiments: 85 cases in the hypoxic pulmonary hypertension (HPH) group, including mil...

journal_title：European review for medical and pharmacological sciences

authors： Han CF,Li ZY,Li TH

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:To compare the inflammatory factors and immune functions of patients with lung cancer and pulmonary ground-glass attenuation. PATIENTS AND METHODS:A total of 108 patients with pulmonary sarcoidosis treated in our hospital were selected and randomly divided into lung cancer group (Group A, n=32), diffuse grou...

journal_title：European review for medical and pharmacological sciences

authors： Liu CY,Xie WG,Wu S,Tian JW,Li J

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:Prostate cancer is a kind of malignancy with high occurrence in the male urogenital system. However, the mechanism of the occurrence, the progression, and the metastasis of prostate cancer are still unclear. Searching for the effective molecule target is of great significance to improve the curative effect on...

journal_title：European review for medical and pharmacological sciences

authors： Song XF,Chang H,Liang Q,Guo ZF,Wu JW

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:Lung cancer is the leading cause of cancer-related mortality. Over 80% of all lung cancer cases are non-small-cell lung cancer (NSCLC) and approximately 5% of NSCLC patients are positive for anaplastic lymphoma kinase (ALK) gene rearrangement or fusion with echinoderm microtubule-associated protein-like 4 (EM...

journal_title：European review for medical and pharmacological sciences

authors： Li G,Dai WR,Shao FC

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:To investigate the relative expression of long non-coding RNA 00673 (lncRNA 00673) in hepatocellular carcinoma (HCC) and HCC cells and study its regulation on the malignant phenotype of HCC cells PATIENTS AND METHODS: Samples of HCC and adjacent tissues from January 2013 to December 2015 were collected. The e...

journal_title：European review for medical and pharmacological sciences

authors： Chen H,Liu JZ,Hu GJ,Shi LL,Lan T

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:Isthmocele represents a reservoir on the anterior wall of the uterine isthmus or of the cervical canal at the site of a previous cesarean delivery scar. Recently, it has been clarified that it might be the cause of several gynecologic symptoms, as most common abnormal uterine bleeding. Hysteroscopy and trans-...

journal_title：European review for medical and pharmacological sciences

authors： Muzii L,Domenici L,Lecce F,Di Feliciantonio M,Frantellizzi R,Marchetti C,Monti M,Benedetti Panici P

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of autophagy on acute myocardial infarction (AMI), and its mechanism in rats. MATERIALS AND METHODS:A total of 75 Sprague Dawley (SD) rats were randomly divided into three groups (n=25): sham operation (S) group, the AMI group and rapamycin (RAPA) treatment group. The model of AMI w...

journal_title：European review for medical and pharmacological sciences

authors： Aisa Z,Liao GC,Shen XL,Chen J,Li L,Jiang SB

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:Over-proliferation of mesangial cells is the major pathological change of mesangial proliferative glomerulonephritis (MPGN). PTEN-PI3K/AKT pathway plays a role in regulating proliferation of mesangial cells. Anti-thymocyte serum nephritis (ATSN) is a widely used animal model for studying MPGN. This study esta...

journal_title：European review for medical and pharmacological sciences

authors： Gao HY,Han CX

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:The aim of this project was to study the imaging characteristics of multi-detector CT (MDCT) in different types of malignant tumor in the common bile duct ampulla. PATIENTS AND METHODS:We examined 30 cases of pancreatic head cancer, 35 of terminal cholangiocarcinoma, 26 of ampullary carcinoma, and 40 of beni...

journal_title：European review for medical and pharmacological sciences

authors： Zhao DZ,Guo Y,Sun YP,Liu HM,Zhang Z,Ma QL,Wang YS,Chen CL

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:Our study aims to demonstrate that the use in the preconceptional period until the 24th week of pregnancy of inositol and folic acid, first of all, preserves the product of conception from neural tube defects (NTDs) and then, thanks to inositol supplementation, it possibly counteracts and prevents the onset o...

journal_title：European review for medical and pharmacological sciences

authors： Dell'Edera D,Sarlo F,Allegretti A,Epifania AA,Simone F,Lupo MG,Benedetto M,D'Apice MR,Capalbo A

更新日期：2017-07-01 00:00:00